Natural Skin Rejuve is one of the pioneering techniques for skin rejuvenation in the modern era of regenerative medicine. Natural Skin Rejuve is generated from one’s own blood by centrifuging it and injecting the Natural Skin Rejuve into the skin. This technique is still pending for FDA approval but has shown exemplary results and a good safety profile. The technique should be done in a standardized manner and using best possible standards of practice. The dermal fibroblasts are responsible for making the collagen and surrounding matrix and is the prime target for Natural Skin Rejuve for its full effect. The expression of MMR1 and MMR3 is increased by Natural Skin Rejuve which stimulates new collagen growth by the fibroblast and the enzymes producing collagen digestion are halted as well. The anti-ageing benefits have not been studied but for all practical purposes, this technique is safer than injectables like Dermal fillers as it is a completely natural treatment.

Indications For Natural Skin Rejuve Treatment

  • Rejuvenation of skin
  • Improving the appearance of fine lines and wrinkles
  • Photoaged skin
  • Acne scars and open pores
  • Sagging skin
  • Dull skin complexion


Contraindications For Natural Skin Rejuve Treatment

  • Patient on blood thinners or bleeding disorders
  • Infection in the treated area
  • Hepatitis B or HIV
  • Any Blood Cancer
  • Patient on immunosuppressants
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Frequently asked questions

We now have an FAQ list that we hope will help you answer some of the more common ones.

1. What are the uses of Natural Skin Rejuve?

Natural Skin Rejuve therapy has been traditionally used in tissue regeneration to promote healing during many procedures in maxillofacial surgery, soft tissue injuries, etc. Natural Skin Rejuve specifically is now been used by dermatologists for management of various alopecias and for skin rejuvenation.

2. How is Natural Skin Rejuve derived?

Natural Skin Rejuve is derived from the centrifugation of the patient’s own blood and it contains growth factors working on different target cells that influence wound healing, thereby playing an important role in tissue repair mechanisms, enhancing soft tissue healing and regeneration at various levels.

3. How does Natural Skin Rejuve work?

Natural Skin Rejuve contains more than 20 types of growth factors which regulate cell migration, proliferation, remodelling of the extracellular matrix (ECM) and promotion of angiogenesis, creating a beneficial environment for enhanced wound healing. More than 1 million/µL of platelet concentration (about four to seven times the mean levels) is therapeutically effective concentration. Concentrations higher or lower than1.5 million platelets/µL inhibit the angiogenic potential in human endothelial cells.

The platelets actively secrete growth factors within 10 minutes after activation and more than ninety five percent of the presynthesized growth factors are secreted within one hour.
Therefore, Natural Skin Rejuve should be used within 10 minutes of activation.

4. What are the contraindications of Natural Skin Rejuve?

01. Absolute contraindications:

  • Platelet dysfunction syndrome
  • Critical thrombocytopenia
  • Hemodynamic instability
  • Septicaemia
  • Local infection
  • Patient unwilling to sign consent.

02. Relative contraindications:

  • Consistent use of NSAIDs within 48 hours of procedure
  • Systemic use of corticosteroids within 2 weeks
  • Heavy Smoking
  • Recent fever/illness
  • Haemoglobin <10>
  • Platelet count <10>

5. Are there any Complications of Natural Skin Rejuve?

Natural Skin Rejuve is a relatively safe procedure. Though minor complications are mentioned as pain in the injected area; headache, heaviness of head, swelling, redness, infection, allergic reaction- urticarial rash, temporary skin discoloration, bruising . Natural Skin Rejuve is autologous and hence no potential side effects compared to pre-existing therapeutic modalities or high degree of compliance. Also, as the mechanism of action of Natural Skin Rejuve is different from other treatments, an additive positive effect may be there on using Natural Skin Rejuve as an adjuvant to minoxidil and finasteride.

6. How many sessions are needed?

The number of sessions depend on the extend of skin problem and hairfall, response to initial therapy and adjuvant treatments. However, in general the treatments are spaced around 4 weeks apart over a period of 4 to 6 months.

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